Saint Jerome completed the translation of the Bible into Latin around 405 AD, known as the Vulgate. This translation became the standard text for Western Christianity for over a millennium, shaping theological discourse and liturgical practices. Jerome's work was instrumental in making the scriptures accessible to a wider audience, influencing Christian thought and the development of the Church.

Saint Jerome's translation of the Vulgate Bible shaped the rhythmic Latin prose that influenced medieval Christian hymnody and mystical poetry. The biblical allusions and moral narratives found in the Vulgate permeated Western literature, inspiring poets such as Dante and Milton to engage with theological themes.