In the 1600s, Spanish missionaries and administrators in the Andean region utilized Quechua to evangelize indigenous populations while promoting Spanish. This dual-language approach aimed to facilitate communication and conversion, reflecting the complexities of colonial interactions. The use of Quechua in religious contexts has had lasting effects on language preservation and cultural identity among indigenous communities.

Spanish policies in Andean indigenous regions since 1600 preserved some indigenous poetic forms in translated texts. Poets like César Vallejo have utilized these translations to explore cultural hybridity and resistance.