In the 1750s, Giacomo Casanova popularized the use of animal intestine condoms, specifically made from sheep intestines, as a means of contraception and disease prevention in Europe. His writings on the subject brought attention to sexual health and practices of the time. This innovation marked a significant step in the history of sexual health, reflecting changing attitudes toward sexuality and personal responsibility.

Casanova's popularization of animal intestine condoms in 1750 became a pivotal symbol of libertine themes in Enlightenment poetry. This shift influenced erotic literature, with poets like John Wilmot exploring the interplay of pleasure, risk, and desire, thus reflecting the broader cultural transformations of the period.