Indigenous Mexican knowledge of herbal abortifacients, such as zoapatle, dates back to around 1500 and played a crucial role in traditional medicine. These plants were used for post-coital contraception, reflecting a deep understanding of botanical properties and reproductive health. The use of herbal remedies highlights the intersection of culture, science, and women's autonomy in historical contexts, influencing contemporary discussions on reproductive rights.

The use of traditional herbal abortifacients in Mexico influenced Latin American poetry, particularly in the magical realist tradition. Poets like Octavio Paz and Sor Juana Inés de la Cruz incorporated themes of healing and resistance, reflecting indigenous wisdom and cultural identity.