In 1272, the practice of alchemy was gaining popularity in Europe, blending science, mysticism, and philosophy. Alchemists sought to transform base metals into gold and discover the elixir of life, reflecting the era's fascination with the natural world and the quest for knowledge. This blend of science and mysticism was particularly influential in the intellectual circles of the time.

The themes of transformation and the pursuit of knowledge found in alchemical practices influenced poets and writers, inspiring works that explored the relationship between science and the mystical. Poets like Dante incorporated alchemical symbolism into their writings, reflecting the era's complex views on nature and existence.