On Easter Monday, April 14, 1817, a group of enslaved people in St. Inigoes, Maryland, near the Jesuit plantation, rose in revolt, attacking their overseers and attempting to escape to freedom. The rebellion, which involved about 40 enslaved people, was quickly suppressed by local militia, and the leaders were executed. The uprising was largely suppressed from public memory by the planter class, but it was one of several slave revolts that occurred in Maryland during the early 19th century. The St. Inigoes rebellion highlighted the ongoing resistance to slavery in the Chesapeake region.

The St. Inigoes rebellion has been rediscovered by historians and has appeared in local historical literature and in works that explore the hidden history of slave resistance in Maryland. The event has been the subject of poems and essays that seek to recover the voices of the enslaved and to challenge the erasure of their stories from official records.